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  • Zachary Cooper, Casey Simons, Silvana Martinin. "Retardation of Crystallization through teh Addition of Dairy Phospholipids" J Am Oil Chem Soc, 2019, X, XX-XX.

  • Subedi, Y. P.; Roberts, P.; Grilley, M. Takemoto, J. Y.; Chang, C.-W. T. “Development of fungal selective amphiphilic kanamycin: cost effective synthesis and use of fluorescent analogs for mode of action investigation" ACS Infect. Diseases, 20195, 473-483. PubMed PMID: 30674192.

  • Alfindee, M.; Subedi, Y. P.; Grilley, M. Takemoto, J. Y.; Chang, C.-W. T. “Antifungal Activities of 4”,6”-Disubstituted Amphiphilic Kanamycins.” Molecules201924, 1882.

  • Subedi, Y. P.; Pandey, U.; Alfindee, M.; Montgomery, H.; Roberts, P.; Wight, J.; Nichols, G. Grilley, M. Takemoto, J. Y.; Chang, C.-W. T. “Scalable and cost-effective tosylation-mediated synthesis of antifungal and fungal diagnostic 6″-Modified amphiphilic kanamycins” Eur. J. Med. Chem2019182, in press (


  • Yan, H., Sun,L., Huang, J., Qiu, Y., Xu, F., Yan, R., Zhu, D., Wang, W., Zhan, J. (2018): Identification and heterologous reconstitution of a 5-alk(en)ylresorcinol synthase from endophytic fungus Shiraia sp. Slf14. Journal of Microbiology 56, (11), 805-812.

  • Fidan, O., Yan, R., Gladstone, G., Zhou, T., Zhu, D., Zhan, J. (2018): New insights into the glycosylation steps in the biosynthesis of Sch47554 and Sch47555. ChemBioChem 19(13), 1424-1432.

  • Alfindee, M.; Zhang, Q.; Subedi, Y. P.; Shrestha, J. P.; Kawsaka, Y.; Grilley, M.; Takemoto, J. Y.; Chang, C.-W. T. “One-step Synthesis of Carbohydrate Esters as Antibacterial and Antifungal Agents.” Bioorg. Med. Chem., 201826, 765-774. PubMed PMID: 29305296.

  • Alfindee, M.; Subedi, Y. P.; Fiori, M. C.; Krishnan, S.; Kjellgren, A.; Altenberg, G. A.; Chang, C.-W. T. “Inhibition of Connexin Hemichannels by New Amphiphilic Amino-glycosides without Antibiotic Activity.” ACS Med. Chem. Lett20189, 697-701. PubMed PMID: 30034603; PubMed Central PMCID: PMC6047172.

  • Subedi, Y. P.; Alfindee, M.; Shrestha, J. P.; Becker, G. Grilley, M. Takemoto, J. Y.; Chang, C.-W. T. “Synthesis and biological activity investigation of azole and quinone hybridized phosphonates.” Bioorg. Med. ChemLett201828, 3034-3037. PubMed PMID: 30093296.

  • Subedi, Y. P.; Alfindee, M.; Shrestha, J. P.; Chang, C.-W. T. “Tuning the Biological Activity of Cationic Anthraquinone Analogues Specifically toward Staphylococcus aureus.” Eur. J. Med. Chem2018157, 683-690. PubMed PMID: 30130717.


  • Yu, D., Xu, F., Zhang, S., Zhan, J.* (2017): Decoding and reprogramming fungal iterative nonribosomal peptide synthetases. Nature Communications 8, 15349.

  • Xu, F., Napan, K., Zhang, S., Gladwin, T., Takemoto, J., Zhan, J.* (2017): New insights into pradimicin biosynthesis revealed by two O-methyltransferases. Bioorganic & Medicinal Chemistry Letters 27(15), 3499–3502.

  • Yuan Chu, Nicholas H. Williams, and Alvan C. Hengge.  “Transition States and Control of Substrate Preference in the Promiscuous Phosphatase PP1.”  Biochemistry2017, 56 (30), 3923-3933.
  •  You, B.; Liu, X.; Liu, X.; Sun, Y.* "Efficient H2 evolution coupled with oxidative refining of alcohols via a hierarchically porous nickel bifunctional electrocatalyst" ACS Catal., 20177, 4564-4570.
  • Jiang, N.; Liu, X.; Dong, J.; You, B.; Liu, X.; Sun, Y.* "Electrocatalysis of furfural oxidation coupled with H2 evolution via nickel-based electrocatalysts in water" ChemNanoMat, 20173, 491-495.

     Zhang, S., Qiu, Y., Kakule, T., Lu, Z., Xu, F., Lamb, J. G., Reilly, C., Zheng, Y., Sham, S. W., Wang, W.,* Xuan, L.-J., Schmidt, E., Zhan, J.* (2017): Identification of cyclic depsipeptides and their dedicated synthetase from Hapsidospora irregularisJournal of Natural Products 80(2), 363–370.

  • Shrestha, J. P.; Baker, C.; Kawasaki, Y.; Subedi, Y. P.; Nziko, V. P.; Takemoto, J. Y.; Chang, C.-W. T. “Synthesis and Bioactivity Investigation of Quinone-based Dimeric Cationic Triazolium Amphiphiles Selective against Resistant Fungal and Bacterial Pathogens.” Eur. J. Med. Chem. 2017, 126, 696-704. PubMed PMID: 27951483.



  • You, B.; Liu, X.; Jiang, N.; Sun, Y.* "A general strategy for decoupled hydrogen production from water splitting by integrating oxidative biomass valorizationJ. Am. Chem. Soc., 2016138, 13639-13646.
  • You, B.; Jiang, N.; Liu, X.; Sun, Y.* "Simultaneous H2 generation and biomass upgrading in water by an efficient noble-metal-free bifunctional electrocatalyst" Angew. Chem. Int. Ed., 201655, 9913-9917.
  • Jiang, N.; You, B.; Boonstra, R.; Terrero Rodriguez, I. M.; Sun, Y.* "Integrating electrocatalytic 5-hydroxymethylfurfural oxidation and hydrogen production via Co-P-derived electrocatalysts" ACS Energy Lett., 20161, 386-390.

  • Zhang, Q.; Alfindee, M.; Shrestha, J. P.; Nziko, V. P.; Kawasaki, Y.; Peng, X.; Takemoto, J. Y.; Chang, C.-W. T. “Divergent Synthesis of Three Classes of Antifungal Amphiphilic Kanamycin Derivatives.” J. Org. Chem. 201681, 10651–10663. PubMed PMID: 27715046.



  • Gwendolyn Moise, Nathan M. Gallup, Anastassia N. Alexandrova, Alvan C. Hengge, and Sean J. Johnson.  “Conservative tryptophan mutants of the protein-tyrosine phosphatase YopH exhibit impaired WPD-loop function and crystallize with divanadate esters in their active sites.”  Biochemistry201554 (42), 6490–6500.

  •  Alvan C. Hengge.  “Kinetic Isotope Effects In The Characterization Of Catalysis by Protein Tyrosine Phosphatases.”  Biochim. Biophys. Acta.-Proteins and Proteomics, 20151854, 1768-1775.  DOI:  10.1016/j.bbapap.2015.03.010. 

  • Zhang, Q.; Peng, X.; Grilley, M.; Takemoto, J. Y.; Chang, C.-W. T. "Using Fluorogenic Probes for the Investigation of Selective Biomass Degradation by Fungi." Green Chem201517, 1918–1925.

  • Zhang, Q.; Chang, C.-W. T. "Divergent and Facile Lewis Acid-Mediated Synthesis of N-Alkyl 2-aminomethylene-1,3-indanediones and 2-Alkylamino-1,4-Naphthoquinones." Tetrahedron Lett. 201556, 893-896.

  • Fosso, M.; AlFindee, M. N.; Zhang, Q.; Nziko, V. P. N.; Kawasaki, Y.; Shrestha, S. K.; Bearss, J.; Gregory, R.; Takemoto, J. Y.; Chang, C.-W. T. “Structure–Activity Relationships for Antibacterial to Antifungal Conversion of Kanamycin to Amphiphilic Analogues.” J. Org. Chem. 201580, 4398–4411. PubMed PMID: 25826012.

  • Shrestha, J. P.; Subedi, Y. P.; Chen, L. L.; Chang, C.-W. T. “Mode of Action Study of Cationic Anthraquinone Analog: A New Class of Highly Potent Anti-cancer Agent.” MedChemComm20156, 2012-2022.