Skip to main content

Scott Ensign

Profile Picture

Biochemistry

Professor


Educational Background

PhD, Biochemistry, University of Wisconsin-Madison, 1991
BS, Chemistry, Brigham Young University, 1986

Awards

Institution Faculty/Staff of the Month Campus Winner, 2014

National Residence Hall Honorary

Utah State University Residents' Choice Award, Best Professor, 2013

USU Housing and residence life

College of Science Advisor of the Year, 2007

USU College of Science

Excellence in instruction for first year students, 2007

Utah State University

Researcher of the Year, 2003

USU College of Science

Eldon J Gardner Award, Teacher of the Year, 2002

Utah State University

Robins Award, Professor of the Year, 2002

Utah State University

Teacher of the Year, 2002

USU College of Science

Valedictorian Escort, 2002

USU College of Science

Research Presentation Award, 1991

Abbott Laboratories

Publications - Abstracts

    Publications - Books & Book Chapters

      * Has not been peer reviewed

      Publications - Fact Sheets

        * Has not been peer reviewed

        Publications - Curriculum

          * Has not been peer reviewed

          Publications - Journal Articles

            Academic Journal

          • Ensign, S.A, (2011). A new pathway for acetate assimilation. Science, 331, 294-295.
          • Pandey, A.S, Mulder, D.W, Ensign, S.A, Peters, J.W, (2011). Structural basis for carbon dioxide binding by 2-ketopropyl coenzyme M oxidoreductase/carboxylase. FEBS Letters, 585, 459-464.
          • Kofoed, M.A, Wampler, D.A, Pandey, A.S, Peters, J.W, Ensign, S.A, (2011). Roles of the redox active disulfide, and histidine residues forming a catalytic dyad, in reactions catalyzed by 2-Ketopropyl-Coenzyme M Oxidoreductase/Carboxylase. The Journal of Bacteriology, 193, 4904-4913.
          • Boyd, J.M, Clark, D.D, Kofoed, M.A, Ensign, S.A, (2010). Mechanism of inhibition of aliphatic epoxide carboxylation by the Coenzyme M analog 2-bromoethanesulfonate. Journal of Biological Chemistry, 285, 25232-25242.
          • Sliwa, D., Krishnakumar, A., Peters, J.W, Ensign, S.A, (2010). Molecular basis for enantioselectivity in the (R)- and (S)-hydroxypropylthioethanesulfonate dehydrogenases, a unique pair of stereoselective short-chain dehydrogenases/reductases involved in aliphatic epoxide carboxylation. Biochemistry, 49, 8831-8840.
          • Krishnakumar, A.M, Sliwa, D., Endrizzi, J.A, Boyd, E.S, Ensign, S.A, Peters, J.W, (2008). Getting a Handle on the Role of Coenzyme M in Alkene Metabolism. Microbiology and Molecular Biology Reviews, 72, 445-456.
          • Boyd, J.M, Ellsworth, A., Ensign, S.A, (2006). Characterization of 2-Bromoethanesulfonate as a Selective Inhibitor of the Coenzyme M-Dependent Pathway and Enzymes of Bacterial Aliphatic Epoxide Metabolism. The Journal of Bacteriology, 188, 8062-8069.
          • Pandev, A.S, Nocek, B., Clark, D.D, Ensign, S.A, Peters, J.W, (2006). Mechanistic Implications of the Structure of the Mixed-Disulfide Intermediate of the Disulfide Oxidoreductase, 2-Ketopropyl-Coenzyme M Oxidoreductase/Carboxylase. Biochemistry, 45, 113-120.
          • Ensign, S.A, (2006). Revisiting the glyoxylate cycle: alternative pathways for microbial acetate assimilation. Molecular Microbiology, 61, 274-276.
          • Krishnakumar, A.M, Nocek, B.P, Clark, D.D, Ensign, S.A, Peters, J.W, (2006). Structural Basis for Stereoselectivity in the (R)- and (S)-Hydroxypropylthioethanesulfonate Dehydrogenases. Biochemistry, 45, 8831-8840.
          • Boyd, J.M, Ensign, S.A, (2005). ATP-dependent Enolization of Acetone by Acetone Carboxylase from Rhodobacter capsulatus. Biochemistry, 44, 8543-8553.
          • Boyd, J.M, Ensign, S.A, (2005). Evidence for a Metal-Thiolate Intermediate in Alkyl Group Transfer from Epoxypropane to Coenzyme M and Cooperative Metal Ion Binding in Epoxyalkane:CoM Transferase. Biochemistry, 44, 13151-13162.
          • Wampler, D.A, Ensign, S.A, (2005). Photoheterotrophic metabolism of Acrylamide by a Newly Isolated Strain of Rhodopseudomonas palustris. Appl. Environ. Microbiol., 71, 5850-5857.
          • Boyd, J.M, Ellsworth, H., Ensign, S.A, (2004). Bacterial acetone carboxylase is a manganese-dependent metalloenzyme. The Journal of Biological Chemistry, 279, 46644-46651.
          • Nocek, B., Boyd, J., Ensign, S.A, Peters, J.W, (2004). Crystallization and preliminary X-ray analysis of an acetone carboxylase from Xanthobacter autotrophicus strain Py2. ACTA CRYSTALLOGRAPHICA D, 60, 385-387.
          • Clark, D.D, Boyd, J.M, Ensign, S.A, (2004). The Stereoselectivity and Catalytic Properties of Xanthobacter autotrophicus 2-[(R)-2-Hydroxypropylthio]ethanesulfonate Dehydrogenase Are Controlled by Interactions between C-Terminal Arginine Residues and the Sulfonate of Coenzyme M. Biochemistry, 43, 6763-6771.
          • Ensign, S.A, Allen, J.R, (2003). Aliphatic Epoxide Carboxylation. Annual Review of Biochemistry, 72, 55-76.
          • Clark, D.D, Ensign, S.A, (2002). Characterization of the 2-[(R)-2-hydroxypropylthio] ethanesulfonate Dehydrogenase from Xanthobacter strain Py2: Product Inhibition, pH-Dependence of Kinetic Parameters, Site-Directed Mutagenesis, Rapid-Equilibrium Inhibition, and Chemical Modification. Biochemistry, 41, 2727-2740.
          • Nocek, B., Clark, D.D, Ensign, S.A, Peters, J.W, (2002). Crystallization and preliminary X-ray analysis of an R-2-hydroxypropyl-coenzyme M dehydrogenase. Acta Crystallographica, 58, 1470-1473.
          • Nocek, B., Jang, S.B, Jeong, M.S, Clark, D.D, Ensign, S.A, Peters, J.W, (2002). Structural basis for CO2 fixation by a novel member of the disulfide oxidoreductase family of enzymes: 2-ketopropyl-Coenzyme M Oxidoreductase/ Carboxylase. Biochemistry, 41, 12907-12913.
          • Sluis, M.K, Larsen, R.A, Krum, J.G, Anderson, R., Metcalf, W.W, Ensign, S.A, (2002). Biochemical, molecular, and genetic analyses of the acetone carboxylases from Xanthobacter autotrophicus strain Py2 and Rhodobacter capsulatus strain B10. J Bacteriol. , 184:11, 2969-2977.
          • Krum, J.G, Ellsworth, H., Sargeant, R.R, Rich, G., Ensign, S.A, (2002). Kinetic and microcalorimetric analysis of substrate and cofactor interactions in epoxyalkane:CoM transferase, a zinc-dependent epoxidase. Biochemistry, 15, 5005-5014.
          • Jang, S.B, Jeong, M.S, Clark, D.D, Ensign, S.A, Peters, J.W, (2001). Characterization and preliminary X-ray analysis of a NADPH:2-ketopropyl-Coenzyme M Oxidoreductase/ Carboxylase. Acta Crystallographica, 57, 445-447.
          • Krum, J.G, Ensign, S.A, (2001). Evidence that a linear megaplasmid in Xanthobacter strain Py2 encodes enzymes of aliphatic alkene and epoxide metabolism and Coenzyme M (2-mercaptoethanesulfonate) biosynthesis. J. Bacteriol. , 183, 2172-2177.
          • Ensign, S.A, (2001). Microbial Metabolism of Aliphatic Alkenes. Biochemistry, 40, 5845-5853.

          * Has not been peer reviewed

          Publications - Literary Journal

            * Has not been peer reviewed

            Publications - MultiMedia

              * Has not been peer reviewed

              Publications - Technical Reports

                * Has not been peer reviewed

                Publications - Translations & Transcripts

                  Publications - Other

                    * Has not been peer reviewed

                    Scheduled Teaching

                    CHEM 1210 - Principles of Chemistry I, Fall 2016

                    CHEM 1210 - Principles of Chemistry I, Fall 2016

                    CHEM 1220 - Principles of Chemistry II, Summer 2016

                    CHEM 1210 - Principles of Chemistry I, Spring 2016

                    CHEM 1220 - Principles of Chemistry II, Spring 2016

                    CHEM 6720 - Principles of Enzymology I, Spring 2016

                    CHEM 4800 - Research Problems, Spring 2016

                    HONR 4900 - Senior Thesis/Project, Spring 2016

                    CHEM 1210 - Principles of Chemistry I, Fall 2015

                    CHEM 1210 - Principles of Chemistry I, Fall 2015

                    CHEM 1210 - Principles of Chemistry I, Fall 2015

                    CHEM 1220 - Principles of Chemistry II, Summer 2015

                    CHEM 1210 - Principles of Chemistry I, Spring 2015

                    CHEM 1220 - Principles of Chemistry II, Spring 2015

                    CHEM 6730 - Principles of Enzymology, Spring 2015

                    CHEM 4800 - Research Problems, Spring 2015

                    CHEM 1210 - Principles of Chemistry I, Fall 2014

                    CHEM 1210 - Principles of Chemistry I, Fall 2014

                    CHEM 4800 - Research Problems, Fall 2014

                    CHEM 1220 - Principles of Chemistry II, Summer 2014

                    CHEM 1210 - Principles of Chemistry I, Spring 2014

                    CHEM 1220 - Principles of Chemistry II, Spring 2014

                    CHEM 7800 - Seminar, Spring 2014

                    CHEM 1210 - Principles of Chemistry I, Fall 2013

                    CHEM 1210 - Principles of Chemistry I, Fall 2013

                    CHEM 4800 - Research Problems, Fall 2013

                    CHEM 7800 - Seminar, Fall 2013

                    CHEM 1220 - Principles of Chemistry II, Summer 2013

                    CHEM 1220 - Principles of Chemistry II, Spring 2013

                    CHEM 6730 - Principles of Enzymology, Spring 2013

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1210 - Principles of Chemistry I, Fall 2012

                    CHEM 1220 - Principles of Chemistry II, Summer 2012

                    CHEM 1220 - Principles of Chemistry II, Spring 2012

                    CHEM 5700,6700 - General Biochemistry I, Fall 2011

                    CHEM 1210 - Principles of Chemistry I, Fall 2011

                    CHEM 1220 - Principles of Chemistry II, Summer 2011

                    CHEM 7970 - DISSERTATION RSRCH, Spring 2011

                    CHEM 6730 - PRIN OF ENZYMOLOGY, Spring 2011

                    CHEM 4800 - RESEARCH PROBLEMS (CI), Spring 2011

                    CHEM 6700 - Advanced Biochemistry I, Fall 2010

                    CHEM 5700 - General Biochemistry I, Fall 2010

                    CHEM 1210 - Principles of Chemistry I, Fall 2010

                    CHEM 1210 - Principles of Chemistry I, Fall 2010

                    CHEM 1210 - Principles of Chemistry I, Fall 2010

                    CHEM 1210 - Principles of Chemistry I, Fall 2010

                    CHEM 1210 - Principles of Chemistry I, Fall 2010

                    CHEM 1210 - Principles of Chemistry I, Fall 2010

                    CHEM 1210 - Principles of Chemistry I, Fall 2010

                    CHEM 1210 - Principles of Chemistry I, Fall 2010

                    CHEM 1210 - Principles of Chemistry I, Fall 2010

                    CHEM 4800 - Research Problems, Fall 2010


                    Graduate Students Mentored

                    Missy Beighley, January 2006 2012
                    Dariusz Sliwa, January 2005 2011