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Tuning the biological activity of cationic anthraquinone analogues specifically toward staphylococcus aureus

Tuning the biological activity of cationic anthraquinone analogues specifically toward staphylococcus aureus

08/18/2018

Yagya Prasad Subedi, madher N. Alfindee, Jaya P. Shestha, and Cheng-Wei Tom Chang Abstract: Development of new antibacterial agents against drug resistant bacteria is an imminent task, especially against methicillin-resistant Staphylococcus aureus (MRSA)....

Synthesis and biological activity investigation of azole and quinone hybridized phosphonates

Synthesis and biological activity investigation of azole and quinone hybridized phosphonates

08/01/2018

Yagya Prasad Subedi, Madher N. Alfindee, Jaya P. Shrestha, Greg Becker, Michelle Grilley, Jon Y. Takemoto, Cheng-Wei Tom Chang ABSTRACT: Phosphonates, azoles and quinones are pharmacophores found in bioactive compounds. A series of phosphonates conjugated...

Inhibition of connexin hemichannels by new amphiphilic aminoglycosides without antibiotic activity

Inhibition of connexin hemichannels by new amphiphilic aminoglycosides without antibiotic activity

06/19/2018

Madher N. Alfindee, Yagya P. Subedi, Mariana C. Fiori, Srinivasan Krishnan, Abbey Kjellgren, Guillermo A. Altenberg, and Cheng-Wei T. Chang ABSTRACT: Connexins hemichannels (HCs) from adjacent cells form gap junctional channels that mediate cell-to-cell c...

Antifungal amphiphilic kanamycins: new life for an old drug

Antifungal amphiphilic kanamycins: new life for an old drug

04/15/2018

Yagya Prasad Subedi, Madher N. Alfinee, Jon Y. Takemoto and Cheng-Wei Tom Chang Classical aminoglycoside antibiotics are obsolete or hampered by the emergence of drug resistant bacteria. Recent discoveries of antifungal amphiphilic kanamycins offer new

Excitonic and confinement effects of 2D layered (C10H21NH3) 2PbBr4 single crystals

Excitonic and confinement effects of 2D layered (C10H21NH3) 2PbBr4 single crystals

03/20/2018

Huatao Yin, Lei Jin, Yuqin Qian, Xia Li, Yuhao Wu, Michael S. Bowen, Deirdre Kaan, Chao He, Derek I Wozniak, Bolei Xu, Asa J Lewis, Weiwei Shen, Ke Chen, Graham E Dobereiner, Yan Zhao, Bradford B Wayland, Yi Rao Recognition of unusual optoelectronic prop

A sulfonate-functionalized viologen enabling neutral cation exchange, aqueous organic redox flow batteries toward renewable energy storage

A sulfonate-functionalized viologen enabling neutral cation exchange, aqueous organic redox flow batteries toward renewable energy storage

02/13/2018

Camden DeBruler, Bo Hu, Jared Moss, Jian Luo, and T. Leo Liu: Redox flow batteries using synthetically tunable and resource abundant organic molecules have gained increasing attention for large-scale energy storage. Herein we report a sulfonate-functional...