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A yoph ptp1b chimera shows the importance of the wpd-loop sequence to the activity, structure, and dynamics of protein tyrosine phosphatases

A yoph ptp1b chimera shows the importance of the wpd-loop sequence to the activity, structure, and dynamics of protein tyrosine phosphatases

08/15/2018

Gwendolyn Moise, Yalemi Morales, Victor Beaumont, Timothy Caradonna, J. Patrick Loria, Sean J. Johnson, and Alvan C. Hengge ABSTRACT: To study factors that affect WPD-loop motion in protein tyrosine phosphatases (PTPs), a chimera of PTP1B and YopH was cre...

Structure of frequency-interacting RNA helicase from neurospora crassa reveals high flexibility in a domain critical for circadian rhythm and RNA surveiillance

Structure of frequency-interacting RNA helicase from neurospora crassa reveals high flexibility in a domain critical for circadian rhythm and RNA surveiillance

05/02/2018

Morales Y., Olsen KJ, Bulcher JM, Johnson SJ ABSTRACT:The FRH (frequency-interacting RNA helicase) protein is the Neurospora crassa homolog of yeast Mtr4, an essential RNA helicase that plays a central role in RNA metabolism as an activator of the nucle

Electrocatalytic CO2 reduction catalyzed by nitrogenase MoFe and FeFe proteins

Electrocatalytic CO2 reduction catalyzed by nitrogenase MoFe and FeFe proteins

04/01/2018

Bo Hu, Derek F. Harris, Dennis R. Dean, T. Leo Liu, Zhi-Yong Yang, Lance C. Seefeldt: Nitrogenases catalyze biological dinitrogen (N2) reduction to ammonia (NH3), and also reduce a number of non-physiological substrates, including carbon dioxide (CO2) to

MxiN differentially regulates monomeric and oligomeric species of the Shigella type three secretion system ATPase Spa47

MxiN differentially regulates monomeric and oligomeric species of the Shigella type three secretion system ATPase Spa47

03/29/2018

Heather B. Case and Nicholas E. Dickenson: Shigella rely entirely on the action of a single type three secretion system (T3SS) to support cellular invasion of colonic epithelial cells and to circumvent host immune responses. The ATPase Spa47 resides at th...

Mechanism of N2 reduction catalyzed by Fe-nitrogenase involves reductive elimination of H2

Mechanism of N2 reduction catalyzed by Fe-nitrogenase involves reductive elimination of H2

02/01/2018

Derek F. Harris, Dmitriy A. Lukoyanov, Sudipta Shaw, Phil Compton, Monika Tokmina-Lukaszewska, Brian Bothner, Neil Kelleher, Dennis R. Dean, Brian M. Hoffman, and Lance C. Seefeldt: Of the three forms of nitrogenase (Mo-nitrogenase, V-nitrogenase, and Fe-...

Phe71 in type III trypanosoomal protein rrginine methyltransferase 7 (TbPRMT7) restricts to monomethylation

Phe71 in type III trypanosoomal protein rrginine methyltransferase 7 (TbPRMT7) restricts to monomethylation

01/29/2018

Tamar B. Caceres, Abhishek Thakur, Owen M Price, Nicole Ippolito, Jun Li, Jun Qu, Orlando Acevedo and Joan Hevel ABSTRACT: Protein arginine methyltransferase 7 (PRMT7) is unique within the PRMT family as it is the only isoform known to exclusively make m

Conformational dynamics of DNA binding and Cas3 recruitment by the CRISPR RNA-guided cascade complex

Conformational dynamics of DNA binding and Cas3 recruitment by the CRISPR RNA-guided cascade complex

10/16/2017

Paul B. G. van Erp, Angela Patterson, Ravi Kant, Luke Berry, Sarah M. Golden, Brittney L. Forsman, Joshua Carter, Ryan N. Jackson, Brian Bothner, and Blake Wiedenheft: Bacteria and archaea rely on CRISPR (clustered regularly interspaced short palindromic

Conformational regulation of CRISPR-associated nucleases

Conformational regulation of CRISPR-associated nucleases

06/15/2017

Jackson, R., van Erp, P.B, Sternberg, S.H, Wiedenheft, B.: Adaptive immune systems in bacteria and archaea rely on small CRISPR-derived RNAs (crRNAs) to guide specialized nucleases to foreign nucleic acids. The activation of these nucleases is controlled

Thermal and elastic characterization of glassy carbon thin films by photoacoustic measurements

Thermal and elastic characterization of glassy carbon thin films by photoacoustic measurements

01/23/2017

D.D. Markushev, J. Ordonez-Miranda, M.D. Rabasovi´c, M. Chirtoc, D.M. Todorovi´c, S.E. Bialkowski, D. Korte, and M. Franko: A portable photoacoustic device is designed and applied to measure thermal diffusivity and linear thermal expansion coefficient of

Melissa Kofoed

Faculty member in the College of Science, Department of Chemistry and Biochemistry